RNS Number : 8386O

Roquefort Therapeutics PLC

04 December 2024

4 December 2024

Roquefort Therapeutics plc

("Roquefort Therapeutics" or the "Company")

Director Share Distribution

Roquefort Therapeutics (LSE:ROQ), the Main Market listed biotech company focused on developing first in class medicines in the high value and high growth immunology and oncology markets, has been advised by VG Corporate Trustee Limited that an employee benefit trust (unrelated to the Company), has been terminated and the trust assets have been distributed to the beneficiaries. As a result of the trust distribution, three Directors of the Company (Ajan Reginald, Dr Darrin Disley and Sir Marin Evans) have received ordinary shares of £0.01 each in the Company ("Ordinary Shares"), as detailed below:

Director	Number of Ordinary Shares Received for Nil Consideration	Number of Ordinary Shares Now Held	% of Company's Issued Capital
Ajan Reginald	34,432	12,346,413	9.1%
Dr Darrin Disley	9,146	2,024,196	1.5%
Sir Martin Evans	2,690	2,690	0.0%

-ENDS-

Enquiries:

Roquefort Therapeutics plc	+44 (0)20 3918 8633
Stephen West (Chairman) / Ajan Reginald (CEO)
SP Angel Corporate Finance LLP (Broker) David Hignell / Vadim Alexandre / Devik Mehta	+44 (0) 20 3470 0470
Burson Buchanan (Public Relations) Ben Romney / Jamie Hooper / George Beale	+44 (0)20 7466 5000
Peak IR (Investor Relations) Seb Wykeham	+33 (0)7 44 44 15 42

LEI: ‎254900P4SISIWOR9RH34

About Roquefort Therapeutics

Roquefort Therapeutics (LSE:ROQ) is a Main Market listed biotech company developing first in class drugs in the high value and high growth immunology and oncology markets prior to partnering with big pharma.

Roquefort Therapeutics' portfolio consists of five novel patent-protected pre-clinical anti-cancer medicines. The highly complementary profile of five best-in-class medicines consists of:

· Midkine antibodies with significant in vivo efficacy and toxicology studies;

· Midkine RNA therapeutics with novel anti-cancer gene editing action;

· Midkine mRNA therapeutics with novel anti-cancer approach;

· STAT-6 siRNA therapeutics targeting solid tumours with significant in vivo efficacy; and

· MK cell therapy with direct and NK cell-mediated anti-cancer action

For further information on Roquefort Therapeutics, please visit www.roquefortplc.com and @RoquefortTherap on X (formerly Twitter).

This announcement contains inside information for the purposes of Article 7 of the UK version of Market Regulation (EU) No 596/2014 on Market Abuse as it forms part of UK domestic law by virtue of the European Union (Withdrawal) Act 2018, as amended ("UK MAR").

The notification below, made in accordance with the requirements of the UK MAR, provides further detail:

NOTIFICATION AND PUBLIC DISCLOSURE OF TRANSACTIONS BY PERSONS DISCHARGING MANAGERIAL RESPONSIBILITIES AND PERSONS CLOSELY ASSOCIATED WITH THEM

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Ajan Reginald
2	Reason for the notification
a)	Position/status	Chief Executive Officer
b)	Initial notification /Amendment	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Roquefort Therapeutics plc
b)	LEI	254900P4SISIWOR9RH34
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares of £0.01 par value ISIN: GB00BMDQ2T15
b)	Nature of the transaction	Trust distribution of 34,432 ordinary shares
c)	Price(s) and volume(s)	Price(s)	Volume(s)
		0 pence per share	34,432
d	Aggregated information - Aggregated volume - Price	- 34,432 - 0p
e)	Date of the transactions	3 December 2024
f)	Place of the transactions	London Stock Exchange (XLON); Main Market

The notification below, made in accordance with the requirements of the UK MAR, provides further detail:

NOTIFICATION AND PUBLIC DISCLOSURE OF TRANSACTIONS BY PERSONS DISCHARGING MANAGERIAL RESPONSIBILITIES AND PERSONS CLOSELY ASSOCIATED WITH THEM

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Dr Darrin Disley
2	Reason for the notification
a)	Position/status	Non-Executive Director
b)	Initial notification /Amendment	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Roquefort Therapeutics plc
b)	LEI	254900P4SISIWOR9RH34
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares of £0.01 par value ISIN: GB00BMDQ2T15
b)	Nature of the transaction	Trust distribution of 9,146 ordinary shares
c)	Price(s) and volume(s)	Price(s)	Volume(s)
		0 pence per share	9,146
d	Aggregated information - Aggregated volume - Price	- 9,146 - 0p
e)	Date of the transactions	3 December 2024
f)	Place of the transactions	London Stock Exchange (XLON); Main Market

The notification below, made in accordance with the requirements of the UK MAR, provides further detail:

NOTIFICATION AND PUBLIC DISCLOSURE OF TRANSACTIONS BY PERSONS DISCHARGING MANAGERIAL RESPONSIBILITIES AND PERSONS CLOSELY ASSOCIATED WITH THEM

1	Details of the person discharging managerial responsibilities / person closely associated
a)	Name	Sir Martin Evans
2	Reason for the notification
a)	Position/status	Non-Executive Director
b)	Initial notification /Amendment	Initial
3	Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor
a)	Name	Roquefort Therapeutics plc
b)	LEI	254900P4SISIWOR9RH34
4	Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted
a)	Description of the financial instrument, type of instrument Identification code	Ordinary shares of £0.01 par value ISIN: GB00BMDQ2T15
b)	Nature of the transaction	Trust distribution of 2,690 ordinary shares
c)	Price(s) and volume(s)	Price(s)	Volume(s)
		0 pence per share	2,690
d	Aggregated information - Aggregated volume - Price	- 2,690 - 0p
e)	Date of the transactions	3 December 2024
f)	Place of the transactions	London Stock Exchange (XLON); Main Market

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